Dendrobium alkaloids prevent Aβ(25–35)-induced neuronal and synaptic loss via promoting neurotrophic factors expression in mice

BACKGROUND: Neuronal and synaptic loss is the most important risk factor for cognitive impairment. Inhibiting neuronal apoptosis and preventing synaptic loss are promising therapeutic approaches for Alzheimer’s disease (AD). In this study, we investigate the protective effects of Dendrobium alkaloid...

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Detalhes bibliográficos
Publicado no:PeerJ
Main Authors: Nie, Jing, Tian, Yong, Zhang, Yu, Lu, Yan-Liu, Li, Li-Sheng, Shi, Jing-Shan
Formato: Artigo
Idioma:Inglês
Publicado em: PeerJ Inc. 2016
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157189/
https://ncbi.nlm.nih.gov/pubmed/27994964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2739
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