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Endothelial repair in stented arteries is accelerated by inhibition of Rho-associated protein kinase

AIMS: Stent deployment causes endothelial cells (EC) denudation, which promotes in-stent restenosis and thrombosis. Thus endothelial regrowth in stented arteries is an important therapeutic goal. Stent struts modify local hemodynamics, however the effects of flow perturbation on EC injury and repair...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cardiovasc Res
Hauptverfasser: Hsiao, Sarah T., Spencer, Tim, Boldock, Luke, Prosseda, Svenja Dannewitz, Xanthis, Ioannis, Tovar-Lopez, Francesco J., Van Beusekom, Heleen M. M., Khamis, Ramzi Y, Foin, Nicolas, Bowden, Neil, Hussain, Adil, Rothman, Alex, Ridger, Victoria, Halliday, Ian, Perrault, Cecile, Gunn, Julian, Evans, Paul C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157135/
https://ncbi.nlm.nih.gov/pubmed/27671802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvw210
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