Cannabinoid signalling inhibits sarcoplasmic Ca(2+) release and regulates excitation–contraction coupling in mammalian skeletal muscle

KEY POINTS: Marijuana was found to cause muscle weakness, although the exact regulatory role of its receptors (CB1 cannabinoid receptor; CB1R) in the excitation–contraction coupling (ECC) of mammalian skeletal muscle remains unknown. We found that CB1R activation or its knockout did not affect muscl...

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Vydáno v:J Physiol
Hlavní autoři: Oláh, Tamás, Bodnár, Dóra, Tóth, Adrienn, Vincze, János, Fodor, János, Reischl, Barbara, Kovács, Adrienn, Ruzsnavszky, Olga, Dienes, Beatrix, Szentesi, Péter, Friedrich, Oliver, Csernoch, László
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Muscle
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157117/
https://ncbi.nlm.nih.gov/pubmed/27641745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272449
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