NR2A-Containing NMDARs in the Prefrontal Cortex Are Required for Working Memory and Associated with Age-Related Cognitive Decline

Working memory, the ability to temporarily maintain representational knowledge, is a foundational cognitive process that can become compromised in aging and neuropsychiatric disease. NMDA receptor (NMDAR) activation in prefrontal cortex (PFC) is necessary for the pyramidal neuron activity believed t...

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Pubblicato in:J Neurosci
Autori principali: McQuail, Joseph A., Beas, B. Sofia, Kelly, Kyle B., Simpson, Kailey L., Frazier, Charles J., Setlow, Barry, Bizon, Jennifer L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157101/
https://ncbi.nlm.nih.gov/pubmed/27807032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2332-16.2016
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