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Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory

Glutamate signaling is essential for the persistent neural activity in prefrontal cortex (PFC) that enables working memory. Metabotropic glutamate receptors (mGluRs) are a diverse class of proteins that modulate excitatory neurotransmission via both presynaptic regulation of extracellular glutamate...

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Publicado en:eNeuro
Autores principales: Hernandez, Caesar M., McQuail, Joseph A., Schwabe, Miranda R., Burke, Sara N., Setlow, Barry, Bizon, Jennifer L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6026020/
https://ncbi.nlm.nih.gov/pubmed/29971246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0164-18.2018
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