Lyme disease spirochaete Borrelia burgdorferi does not require thiamin

Thiamin pyrophosphate (ThDP), the active form of thiamin (vitamin B(1)), is believed to be an essential cofactor for all living organisms(1,2). Here, we report the unprecedented result that thiamin is dispensable for the growth of the Lyme disease pathogen Borrelia burgdorferi (Bb)(3). Bb lacks gene...

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Vydáno v:Nat Microbiol
Hlavní autoři: Zhang, Kai, Bian, Jiang, Deng, Yijie, Smith, Alexis, Nunez, Roy E., Li, Michael B., Pal, Utpal, Yu, Ai-Ming, Qiu, Weigang, Ealick, Steven E., Li, Chunhao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157048/
https://ncbi.nlm.nih.gov/pubmed/27869793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.213
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