Lyme disease spirochaete Borrelia burgdorferi does not require thiamin

Thiamin pyrophosphate (ThDP), the active form of thiamin (vitamin B(1)), is believed to be an essential cofactor for all living organisms(1,2). Here, we report the unprecedented result that thiamin is dispensable for the growth of the Lyme disease pathogen Borrelia burgdorferi (Bb)(3). Bb lacks gene...

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Publicado en:Nat Microbiol
Main Authors: Zhang, Kai, Bian, Jiang, Deng, Yijie, Smith, Alexis, Nunez, Roy E., Li, Michael B., Pal, Utpal, Yu, Ai-Ming, Qiu, Weigang, Ealick, Steven E., Li, Chunhao
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157048/
https://ncbi.nlm.nih.gov/pubmed/27869793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.213
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