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Biological characteristics comparison of HBV rtA181T mutants with truncated or substituted HBsAg expression in vitro and in vivo model systems

The hepatitis B virus(HBV) polymerase rtA181T mutation is selected during long-term antiviral therapy. As the polymerase gene completely overlaps with the envelope (S) gene, HBV rtA181T mutation also carries sW172 mutations. In this study, we investigated whether there were biological differences be...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Zhou, Ling-Yun, Chen, En-Qiang, Wang, Meng-Lan, Chen, Lan-Lan, Liu, Cui-Ping, Zeng, Fan, Tang, Hong
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5157016/
https://ncbi.nlm.nih.gov/pubmed/27976732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39260
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