Regulation of WNT Signaling by VSX2 During Optic Vesicle Patterning in Human Induced Pluripotent Stem Cells

Few gene targets of Visual System Homeobox 2 (VSX2) have been identified despite its broad and critical role in the maintenance of neural retina (NR) fate during early retinogenesis. We performed VSX2 ChIP-seq and ChIP-PCR assays on early stage optic vesicle-like structures (OVs) derived from human...

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Udgivet i:Stem Cells
Main Authors: Capowski, Elizabeth E, Wright, Lynda S, Liang, Kun, Phillips, M. Joseph, Wallace, Kyle, Petelinsek, Anna, Hagstrom, Anna, Pinilla, Isabel, Borys, Katarzyna, Lien, Jessica, Min, Jee Hong, Keles, Sunduz, Thomson, James A, Gamm, David M
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156591/
https://ncbi.nlm.nih.gov/pubmed/27301076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.2414
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