Loss of MITF expression during human embryonic stem cell differentiation disrupts retinal pigment epithelium development and optic vesicle cell proliferation

Microphthalmia-associated transcription factor (MITF) is a master regulator of pigmented cell survival and differentiation with direct transcriptional links to cell cycle, apoptosis and pigmentation. In mouse, Mitf is expressed early and uniformly in optic vesicle (OV) cells as they evaginate from t...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Capowski, Elizabeth E., Simonett, Joseph M., Clark, Eric M., Wright, Lynda S., Howden, Sara E., Wallace, Kyle A., Petelinsek, Anna M., Pinilla, Isabel, Phillips, M. Joseph, Meyer, Jason S., Schneider, Bernard L., Thomson, James A., Gamm, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4222367/
https://ncbi.nlm.nih.gov/pubmed/25008112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu351
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