A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is an inherited disease of the heart muscle characterized by otherwise unexplained thickening of the left ventricle. Left ventricular outflow tract (LVOT) obstruction is present in approximately two-thirds of patients and substantially increases the risk of disease...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Stern, Joshua A., Markova, Svetlana, Ueda, Yu, Kim, Jae B., Pascoe, Peter J., Evanchik, Marc J., Green, Eric M., Harris, Samantha P.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156432/
https://ncbi.nlm.nih.gov/pubmed/27973580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168407
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