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A Small Molecule Inhibitor of Sarcomere Contractility Acutely Relieves Left Ventricular Outflow Tract Obstruction in Feline Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is an inherited disease of the heart muscle characterized by otherwise unexplained thickening of the left ventricle. Left ventricular outflow tract (LVOT) obstruction is present in approximately two-thirds of patients and substantially increases the risk of disease...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Stern, Joshua A., Markova, Svetlana, Ueda, Yu, Kim, Jae B., Pascoe, Peter J., Evanchik, Marc J., Green, Eric M., Harris, Samantha P.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5156432/
https://ncbi.nlm.nih.gov/pubmed/27973580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168407
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