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Reprogramming antitumor immunity against chemoresistant ovarian cancer by a CXCR4 antagonist-armed viral oncotherapy

Ovarian cancer remains the most lethal gynecologic malignancy owing to late detection, intrinsic and acquired chemoresistance, and remarkable heterogeneity. Here, we explored approaches to inhibit metastatic growth of murine and human ovarian tumor variants resistant to paclitaxel and carboplatin by...

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Detalhes bibliográficos
Publicado no:Mol Ther Oncolytics
Main Authors: Komorowski, Marcin P, McGray, AJ Robert, Kolakowska, Agnieszka, Eng, Kevin, Gil, Margaret, Opyrchal, Mateusz, Litwinska, Bogumila, Nemeth, Michael J, Odunsi, Kunle O, Kozbor, Danuta
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155641/
https://ncbi.nlm.nih.gov/pubmed/28035333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mto.2016.34
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