The accessory proteins REEP5 and REEP6 refine CXCR1-mediated cellular responses and lung cancer progression

Some G-protein-coupled receptors have been reported to require accessory proteins with specificity for proper functional expression. In this study, we found that CXCR1 interacted with REEP5 and REEP6, but CXCR2 did not. Overexpression of REEP5 and REEP6 enhanced IL-8-stimulated cellular responses th...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Park, Cho Rong, You, Dong-Joo, Park, Sumi, Mander, Sunam, Jang, Da-Eun, Yeom, Su-Cheong, Oh, Seong-Hyun, Ahn, Curie, Lee, Sang Heon, Seong, Jae Young, Hwang, Jong-Ik
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155276/
https://ncbi.nlm.nih.gov/pubmed/27966653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39041
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