The 5′UTR variant of ERCC5 fails to influence outcomes in ovarian and lung cancer patients undergoing treatment with platinum-based drugs

The common polymorphic variant in the 5′ untranslated region of the excision repair cross-complementation group 5 (ERCC5) gene was described to generate an upstream open reading frame that regulates both the basal ERCC5 expression and its ability to be synthesized following DNA damage. This variant...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Rulli, Eliana, Guffanti, Federica, Caiola, Elisa, Ganzinelli, Monica, Damia, Giovanna, Garassino, Marina C., Piva, Sheila, Ceppi, Lorenzo, Broggini, Massimo, Marabese, Mirko
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5155271/
https://ncbi.nlm.nih.gov/pubmed/27966655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39217
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