Mitochondrial peroxiredoxins are essential in regulating the relationship between Drosophila immunity and aging

Previously, we have shown that flies under-expressing the two mitochondrial peroxiredoxins (Prxs), dPrx3 and dPrx5, display increases in tissue-specific apoptosis and dramatically shortened life span, associated with a redox crisis, manifested as changes in GSH:GSSG and accumulation of protein mixed...

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Publicat a:Biochim Biophys Acta
Autors principals: Odnokoz, Olena, Nakatsuka, Kyle, Klichko, Vladimir I., Nguyen, Jacqueline, Solis, Liz Calderon, Ostling, Kaitlin, Badinloo, Marziyeh, Orr, William C., Radyuk, Svetlana N.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154953/
https://ncbi.nlm.nih.gov/pubmed/27770625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.10.017
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