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Hyperoxidation of Peroxiredoxins and Effects on Physiology of Drosophila

The catalytic activity of peroxiredoxins (Prx) is determined by the conserved peroxidatic cysteine (Cys(P)), which reacts with peroxides to form sulfenic acid (Cys-SOH). Under conditions of oxidative stress, Cys(P) is oxidized to catalytically inactive sulfinic (Cys-SO(2)) and sulfonic (Cys-SO(3)) f...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: McGinnis, Austin, Klichko, Vladimir I., Orr, William C., Radyuk, Svetlana N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071185/
https://ncbi.nlm.nih.gov/pubmed/33920774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040606
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