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Hyperoxidation of Peroxiredoxins and Effects on Physiology of Drosophila

The catalytic activity of peroxiredoxins (Prx) is determined by the conserved peroxidatic cysteine (Cys(P)), which reacts with peroxides to form sulfenic acid (Cys-SOH). Under conditions of oxidative stress, Cys(P) is oxidized to catalytically inactive sulfinic (Cys-SO(2)) and sulfonic (Cys-SO(3)) f...

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Bibliografiske detaljer
Udgivet i:Antioxidants (Basel)
Main Authors: McGinnis, Austin, Klichko, Vladimir I., Orr, William C., Radyuk, Svetlana N.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8071185/
https://ncbi.nlm.nih.gov/pubmed/33920774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox10040606
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