Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

Understanding the host immune response to vaginal exposure to RNA viruses is required to combat sexual transmission of this class of pathogens. In this study, using lymphocytic choriomeningitis virus (LCMV) and Zika virus (ZIKV) in wild-type mice, we show that these viruses replicate in the vaginal...

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Udgivet i:J Exp Med
Main Authors: Khan, Shahzada, Woodruff, Erik M., Trapecar, Martin, Fontaine, Krystal A., Ezaki, Ashley, Borbet, Timothy C., Ott, Melanie, Sanjabi, Shomyseh
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2016
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154948/
https://ncbi.nlm.nih.gov/pubmed/27852793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161289
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