Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

Understanding the host immune response to vaginal exposure to RNA viruses is required to combat sexual transmission of this class of pathogens. In this study, using lymphocytic choriomeningitis virus (LCMV) and Zika virus (ZIKV) in wild-type mice, we show that these viruses replicate in the vaginal...

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Bibliografiska uppgifter
I publikationen:J Exp Med
Huvudupphovsmän: Khan, Shahzada, Woodruff, Erik M., Trapecar, Martin, Fontaine, Krystal A., Ezaki, Ashley, Borbet, Timothy C., Ott, Melanie, Sanjabi, Shomyseh
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2016
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154948/
https://ncbi.nlm.nih.gov/pubmed/27852793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161289
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