Dampened antiviral immunity to intravaginal exposure to RNA viral pathogens allows enhanced viral replication

Understanding the host immune response to vaginal exposure to RNA viruses is required to combat sexual transmission of this class of pathogens. In this study, using lymphocytic choriomeningitis virus (LCMV) and Zika virus (ZIKV) in wild-type mice, we show that these viruses replicate in the vaginal...

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Dettagli Bibliografici
Pubblicato in:J Exp Med
Autori principali: Khan, Shahzada, Woodruff, Erik M., Trapecar, Martin, Fontaine, Krystal A., Ezaki, Ashley, Borbet, Timothy C., Ott, Melanie, Sanjabi, Shomyseh
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154948/
https://ncbi.nlm.nih.gov/pubmed/27852793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161289
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