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Human dendritic cells (DCs) are derived from distinct circulating precursors that are precommitted to become CD1c(+) or CD141(+) DCs

In humans, conventional dendritic cells (cDCs) exist as two unique populations characterized by expression of CD1c and CD141. cDCs arise from increasingly restricted but well-defined bone marrow progenitors that include the common DC progenitor that differentiates into the pre-cDC, which is the dire...

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Bibliographic Details
Published in:J Exp Med
Main Authors: Breton, Gaëlle, Zheng, Shiwei, Valieris, Renan, Tojal da Silva, Israel, Satija, Rahul, Nussenzweig, Michel C.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154947/
https://ncbi.nlm.nih.gov/pubmed/27864467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161135
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