Transcriptome profiling of equine vitamin E deficient neuroaxonal dystrophy identifies upregulation of liver X receptor target genes

Specific spontaneous heritable neurodegenerative diseases have been associated with lower serum and cerebrospinal fluid α-tocopherol (α-TOH) concentrations. Equine neuroaxonal dystrophy (eNAD) has similar histologic lesions to human ataxia with vitamin E deficiency caused by mutations in the α-TOH t...

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Publicado no:Free Radic Biol Med
Main Authors: Finno, Carrie J., Bordbari, Matthew H., Valberg, Stephanie J., Lee, David, Herron, Josi, Hines, Kelly, Monsour, Tamer, Scott, Erica, Bannasch, Danika L., Mickelson, James, Xu, Libin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154892/
https://ncbi.nlm.nih.gov/pubmed/27751910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2016.10.009
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