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Proteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and altered cysteine metabolic pathways

Equine myofibrillar myopathy (MFM) causes exertional muscle pain and is characterized by myofibrillar disarray and ectopic desmin aggregates of unknown origin. To investigate the pathophysiology of MFM, we compared resting and 3 h postexercise transcriptomes of gluteal muscle and the resting skeleta...

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Publicat a:Physiol Genomics
Autors principals: Valberg, Stephanie J., Perumbakkam, Sudeep, McKenzie, Erica C., Finno, Carrie J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337024/
https://ncbi.nlm.nih.gov/pubmed/30289745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00044.2018
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