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Proteome and transcriptome profiling of equine myofibrillar myopathy identifies diminished peroxiredoxin 6 and altered cysteine metabolic pathways

Equine myofibrillar myopathy (MFM) causes exertional muscle pain and is characterized by myofibrillar disarray and ectopic desmin aggregates of unknown origin. To investigate the pathophysiology of MFM, we compared resting and 3 h postexercise transcriptomes of gluteal muscle and the resting skeleta...

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Valberg, Stephanie J., Perumbakkam, Sudeep, McKenzie, Erica C., Finno, Carrie J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337024/
https://ncbi.nlm.nih.gov/pubmed/30289745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00044.2018
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