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Conformational insight into multi-protein signaling assemblies by hydrogen-deuterium exchange mass spectrometry

Hydrogen-deuterium exchange (HDX) mass spectrometry (MS) can provide information about proteins that can be challenging to obtain by other means. Structure/function relationships, binding interactions, and the effects of modification have all been measured with HDX MS for a diverse and growing array...

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Détails bibliographiques
Publié dans:Curr Opin Struct Biol
Auteurs principaux: Harrison, Rane A., Engen, John R.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154849/
https://ncbi.nlm.nih.gov/pubmed/27552080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2016.08.003
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