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Genetics of Gigantism and Acromegaly
Gigantism and acromegaly are rare disorders that are caused by excessive GH secretion and/or high levels of its mediator, IGF-1. Gigantism occurs when excess GH or IGF-1 lead to increased linear growth, before the end of puberty and epiphyseal closure. The majority of cases arise from a benign GH-se...
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| Published in: | Growth Horm IGF Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5154831/ https://ncbi.nlm.nih.gov/pubmed/27657986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ghir.2016.08.002 |
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