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Parkin elimination of mitochondria is important for maintenance of lens epithelial cell ROS levels and survival upon oxidative stress exposure

Age-related cataract is associated with oxidative stress and death of lens epithelial cells (LECs) whose survival is dependent on functional mitochondrial populations. Oxidative stress-induced depolarization/damage of LEC mitochondria results in increased reactive oxygen species (ROS) levels and cel...

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Bibliographic Details
Published in:Biochim Biophys Acta
Main Authors: Brennan, Lisa, Khoury, Josef, Kantorow, Marc
Format: Artigo
Language:Inglês
Published: 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154830/
https://ncbi.nlm.nih.gov/pubmed/27702626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.09.020
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