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Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding.

Myogenin belongs to a family of regulatory factors that can activate myogenesis when transfected into nonmyogenic cells. A conserved DNA sequence, known as an E box, serves as the target for binding and trans-activation by myogenin. Using 10T1/2 fibroblasts that constitutively express a transfected...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Brennan, T J, Edmondson, D G, Li, L, Olson, E N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51545/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1850837/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3822
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