GDF11 Protects against Endothelial Injury and Reduces Atherosclerotic Lesion Formation in Apolipoprotein E-Null Mice

Growth differentiation factor 11 (GDF11) reduces cardiac hypertrophy, improves cerebral vasculature and enhances neurogenesis in ageing mice. Higher growth differentiation factor 11/8 (GDF11/8) is associated with lower risk of cardiovascular events in humans. Here, we showed that adeno-associated vi...

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Publicat a:Mol Ther
Autors principals: Mei, Wen, Xiang, Guangda, Li, Yixiang, Li, Huan, Xiang, Lingwei, Lu, Junyan, Xiang, Lin, Dong, Jing, Liu, Min
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154476/
https://ncbi.nlm.nih.gov/pubmed/27502608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.160
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