A role of stochastic phenotype switching in generating mosaic endothelial cell heterogeneity

Previous studies have shown that biological noise may drive dynamic phenotypic mosaicism in isogenic unicellular organisms. However, there is no evidence for a similar mechanism operating in metazoans. Here we show that the endothelial-restricted gene, von Willebrand factor (VWF), is expressed in a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Yuan, Lei, Chan, Gary C., Beeler, David, Janes, Lauren, Spokes, Katherine C., Dharaneeswaran, Harita, Mojiri, Anahita, Adams, William J., Sciuto, Tracey, Garcia-Cardeña, Guillermo, Molema, Grietje, Kang, Peter M., Jahroudi, Nadia, Marsden, Philip A., Dvorak, Ann, Regan, Erzsébet Ravasz, Aird, William C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154372/
https://ncbi.nlm.nih.gov/pubmed/26744078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10160
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