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The different tissue transcription patterns of genes for HNF-1, C/EBP, HNF-3, and HNF-4, protein factors that govern liver-specific transcription.

The transcription factors that act in hepatocyte-specific gene expression include proteins that are present mainly in liver cells (HNF-1/LFB1, C/EBP, HNF-3, HNF-4) (HNF, hepatocyte nuclear factor; C/EBP, rat enhancer binding protein) and proteins that are widely distributed (AP-1, NF-1, NF-Y/ACF). W...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Xanthopoulos, K G, Prezioso, V R, Chen, W S, Sladek, F M, Cortese, R, Darnell, J E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51542/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2023930/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3807
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