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Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter.

The aldolase B proximal promoter is controlled by at least five elements spanning from -190 to -103 bp with respect to the start site of transcription. From 5' to 3', we found: a negative DE element, an activating C/EBP-DBP binding site, a CCAAT box binding NFY that seems to play a negative role, an...

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Pubblicato in:Nucleic Acids Res
Autori principali: Gregori, C, Kahn, A, Pichard, A L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 1993
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309222/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383844/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/21.4.897
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