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Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter.

The aldolase B proximal promoter is controlled by at least five elements spanning from -190 to -103 bp with respect to the start site of transcription. From 5' to 3', we found: a negative DE element, an activating C/EBP-DBP binding site, a CCAAT box binding NFY that seems to play a negativ...

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Main Authors: Gregori, C, Kahn, A, Pichard, A L
格式: Artigo
語言:Inglês
出版: 1993
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC309222/
https://ncbi.nlm.nih.gov/pubmed/8383844
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