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Non-coding single nucleotide variants affecting estrogen receptor binding and activity

BACKGROUND: Estrogen receptor (ER) activity is critical for the development and progression of the majority of breast cancers. It is known that ER is differentially bound to DNA leading to transcriptomic and phenotypic changes in different breast cancer models. We investigated whether single nucleot...

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Pubblicato in:Genome Med
Autori principali: Bahreini, Amir, Levine, Kevin, Santana-Santos, Lucas, Benos, Panayiotis V., Wang, Peilu, Andersen, Courtney, Oesterreich, Steffi, Lee, Adrian V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154163/
https://ncbi.nlm.nih.gov/pubmed/27964748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-016-0382-0
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