Rare and common epilepsies converge on a shared gene regulatory network providing opportunities for novel antiepileptic drug discovery

BACKGROUND: The relationship between monogenic and polygenic forms of epilepsy is poorly understood and the extent to which the genetic and acquired epilepsies share common pathways is unclear. Here, we use an integrated systems-level analysis of brain gene expression data to identify molecular netw...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Genome Biol
Päätekijät: Delahaye-Duriez, Andree, Srivastava, Prashant, Shkura, Kirill, Langley, Sarah R., Laaniste, Liisi, Moreno-Moral, Aida, Danis, Bénédicte, Mazzuferi, Manuela, Foerch, Patrik, Gazina, Elena V., Richards, Kay, Petrou, Steven, Kaminski, Rafal M., Petretto, Enrico, Johnson, Michael R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2016
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5154105/
https://ncbi.nlm.nih.gov/pubmed/27955713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1097-7
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