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Exchanges of genomic domains between poliovirus and other cocirculating species C enteroviruses reveal a high degree of plasticity

The attenuated Sabin strains contained in the oral poliomyelitis vaccine are genetically unstable, and their circulation in poorly immunized populations can lead to the emergence of pathogenic circulating vaccine-derived polioviruses (cVDPVs). The recombinant nature of most cVDPV genomes and the pre...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Bessaud, Maël, Joffret, Marie-Line, Blondel, Bruno, Delpeyroux, Francis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153852/
https://ncbi.nlm.nih.gov/pubmed/27958320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38831
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