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Exchanges of genomic domains between poliovirus and other cocirculating species C enteroviruses reveal a high degree of plasticity

The attenuated Sabin strains contained in the oral poliomyelitis vaccine are genetically unstable, and their circulation in poorly immunized populations can lead to the emergence of pathogenic circulating vaccine-derived polioviruses (cVDPVs). The recombinant nature of most cVDPV genomes and the pre...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Bessaud, Maël, Joffret, Marie-Line, Blondel, Bruno, Delpeyroux, Francis
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153852/
https://ncbi.nlm.nih.gov/pubmed/27958320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38831
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