טוען...
Improved genome-scale multi-target virtual screening via a novel collaborative filtering approach to cold-start problem
Conventional one-drug-one-gene approach has been of limited success in modern drug discovery. Polypharmacology, which focuses on searching for multi-targeted drugs to perturb disease-causing networks instead of designing selective ligands to target individual proteins, has emerged as a new drug disc...
שמור ב:
| הוצא לאור ב: | Sci Rep |
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| Main Authors: | , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5153628/ https://ncbi.nlm.nih.gov/pubmed/27958331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38860 |
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