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Exploring Landscape of Drug-Target-Pathway-Side Effect Associations

Side effects are the second and the fourth leading causes of drug attrition and death in the US. Thus, accurate prediction of side effects and understanding their mechanism of action will significantly impact drug discovery and clinical practice. Here, we show REMAP, a neighborhood-regularized weigh...

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Bibliografiske detaljer
Udgivet i:AMIA Jt Summits Transl Sci Proc
Main Authors: Lim, Hansaim, Poleksic, Aleksandar, Xie, Lei
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Informatics Association 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5961812/
https://ncbi.nlm.nih.gov/pubmed/29888057
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