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Broken TALEs: Transcription Activator-like Effectors Populate Partly Folded States
Transcription activator-like effector proteins (TALEs) contain large numbers of repeats that bind double-stranded DNA, wrapping around DNA to form a continuous superhelix. Since unbound TALEs retain superhelical structure, it seems likely that DNA binding requires a significant structural distortion...
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| Published in: | Biophys J |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Biophysical Society
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5153609/ https://ncbi.nlm.nih.gov/pubmed/27926841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.10.013 |
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