Suppression of CRTC2-mediated hepatic gluconeogenesis by TRAF6 contributes to hypoglycemia in septic shock

Although hypoglycemia has been documented as a major cause of high mortality in the setting of septic shock, the mechanism of hypoglycemia in infection has not been clearly determined. Hepatic gluconeogenesis serves as an important mechanism to maintain glucose levels under physiological conditions...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Discov
Main Authors: Lv, Sihan, Qiu, Xinchen, Li, Jian, Li, Weida, Zhang, Chao, Zhang, Zhen-Ning, Luan, Bing
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5153457/
https://ncbi.nlm.nih.gov/pubmed/27990298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2016.46
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