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Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease

Our understanding of cardiac fibroblast functions has moved beyond their roles in heart structure and extracellular matrix generation, and now includes contributions to paracrine, mechanical and electrical signalling during ontogenesis and normal cardiac activity. Fibroblasts have central roles in p...

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Bibliografiska uppgifter
I publikationen:Nat Rev Drug Discov
Huvudupphovsmän: Gourdie, Robert G., Dimmeler, Stefanie, Kohl, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152911/
https://ncbi.nlm.nih.gov/pubmed/27339799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.89
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