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Novel therapeutic strategies targeting fibroblasts and fibrosis in heart disease
Our understanding of cardiac fibroblast functions has moved beyond their roles in heart structure and extracellular matrix generation, and now includes contributions to paracrine, mechanical and electrical signalling during ontogenesis and normal cardiac activity. Fibroblasts have central roles in p...
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| Publicado no: | Nat Rev Drug Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152911/ https://ncbi.nlm.nih.gov/pubmed/27339799 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.89 |
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