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Site-specific mutagenesis of Drosophila proliferating cell nuclear antigen enhances its effects on calf thymus DNA polymerase δ

BACKGROUND: We and others have shown four distinct and presumably related effects of mammalian proliferating cell nuclear antigen (PCNA) on DNA synthesis catalyzed by mammalian DNA polymerase δ(pol δ). In the presence of homologous PCNA, pol δ exhibits 1) increased absolute activity; 2) increased pr...

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Main Authors: Mozzherin, Dmitry Ju, McConnell, Maeve, Miller, Holly, Fisher, Paul A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC515284/
https://ncbi.nlm.nih.gov/pubmed/15310391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2091-5-13
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