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Structural characterization of missense mutations using high resolution mass spectrometry: A case study of the Parkinson’s-related protein, DJ-1
Missense mutations that lead to the expression of mutant proteins carrying single amino acid substitutions are the cause of numerous diseases. Unlike gene lesions, insertions, deletions, nonsense mutations or modified RNA splicing, which affect the length of a polypeptide, or determine whether a pol...
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| Publicado no: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152731/ https://ncbi.nlm.nih.gov/pubmed/27048419 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-016-1379-z |
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