Novel expression of a functional trimeric fragment of human SP-A with efficacy in neutralisation of RSV

Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis and hospitalisation of infants in developed countries. Surfactant protein A (SP-A) is an important innate immune molecule, localized in pulmonary surfactant. SP-A binds to carbohydrates on the surface of pathogens in a calcium-d...

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Publicado no:Immunobiology
Main Authors: Watson, Alastair, Kronqvist, Nina, Spalluto, C. Mirella, Griffiths, Mark, Staples, Karl J., Wilkinson, Tom, Holmskov, Uffe, Sorensen, Grith L., Rising, Anna, Johansson, Jan, Madsen, Jens, Clark, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5152705/
https://ncbi.nlm.nih.gov/pubmed/27793398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2016.10.015
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