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The use of retroviral vectors for gene therapy-what are the risks? A review of retroviral pathogenesis and its relevance to retroviral vector-mediated gene delivery

Retroviral vector-mediated gene transfer has been central to the development of gene therapy. Retroviruses have several distinct advantages over other vectors, especially when permanent gene transfer is the preferred outcome. The most important advantage that retroviral vectors offer is their abilit...

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Bibliografiske detaljer
Hovedforfatter: Anson, Donald S
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC515179/
https://ncbi.nlm.nih.gov/pubmed/15310406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-2-9
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