Intracellular heterogeneity in mitochondrial membrane potentials revealed by a J-aggregate-forming lipophilic cation JC-1.

By using a potential-dependent J-aggregate-forming delocalized lipophilic cation, 5,5',6,6'-tetrachloro-1,1',3,3'-tetraethylbenzimidazolocarbocyanine++ + iodide (JC-1), we find that membrane potentials across mitochondria in a living cell can be heterogeneous. Remarkably, even wi...

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Bibliographic Details
Main Authors: Smiley, S T, Reers, M, Mottola-Hartshorn, C, Lin, M, Chen, A, Smith, T W, Steele, G D, Chen, L B
Format: Artigo
Language:Inglês
Published: 1991
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC51514/
https://ncbi.nlm.nih.gov/pubmed/2023917
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