Chargement en cours...
Identification of an Orally Efficacious GPR40/FFAR1 Receptor Agonist
[Image: see text] GPR40/FFAR1 is a G protein-coupled receptor predominantly expressed in pancreatic β-cells and activated by long-chain free fatty acids, mediating enhancement of glucose-stimulated insulin secretion. A novel series of substituted 3-(4-aryloxyaryl)propanoic acid derivatives were prep...
Enregistré dans:
| Publié dans: | ACS Med Chem Lett |
|---|---|
| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2016
|
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5150676/ https://ncbi.nlm.nih.gov/pubmed/27994752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.6b00331 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|