Selective Coactivator Interactions in Gene Activation by SREBP-1a and -1c

Requisite levels of intracellular cholesterol and fatty acids are maintained in part by the sterol regulatory element binding proteins (SREBPs). Three major SREBP isoforms exist; SREBP-1a and SREBP-1c are expressed from overlapping mRNAs, whereas SREBP-2 is encoded by a separate gene. The active for...

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Bibliographic Details
Main Authors: Toth, Julia I., Datta, Shrimati, Athanikar, Jyoti N., Freedman, Leonard P., Osborne, Timothy F.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC515064/
https://ncbi.nlm.nih.gov/pubmed/15340088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.18.8288-8300.2004
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