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Isolated pores dissected from human two-pore channel 2 are functional

Multi-domain voltage-gated ion channels appear to have evolved through sequential rounds of intragenic duplication from a primordial one-domain precursor. Whereas modularity within one-domain symmetrical channels is established, little is known about the roles of individual regions within more compl...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Penny, Christopher J., Rahman, Taufiq, Sula, Altin, Miles, Andrew J., Wallace, B. A., Patel, Sandip
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150636/
https://ncbi.nlm.nih.gov/pubmed/27941820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38426
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