Inhibition of the processing of miR-25 by HIPK2-Phosphorylated-MeCP2 induces NOX4 in early diabetic nephropathy

Phosphorylated methyl-CpG binding protein2 (p-MeCP2) suppresses the processing of several microRNAs (miRNAs). Homeo-domain interacting protein kinase2 (HIPK2) phosphorylates MeCP2, a known transcriptional repressor. However, it is not known if MeCP2 and HIPK2 are involved in processing of miRNAs imp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Oh, Hyung Jung, Kato, Mitsuo, Deshpande, Supriya, Zhang, Erli, Sadhan, Das, Lanting, Linda, Wang, Mei, Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5150532/
https://ncbi.nlm.nih.gov/pubmed/27941951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38789
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