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Cell cycle-specific effects of lovastatin.

Lovastatin (LOV), the drug recently introduced to treat hypercholesteremia, inhibits the synthesis of mevalonic acid. The effects of LOV on the cell cycle progression of the human bladder carcinoma T24 cell line expressing activated p21ras were investigated. At a concentration of 2-10 microM, LOV ar...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Jakóbisiak, M, Bruno, S, Skierski, J S, Darzynkiewicz, Z
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51505/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1673788/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.9.3628
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