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Cell cycle-specific effects of lovastatin.

Lovastatin (LOV), the drug recently introduced to treat hypercholesteremia, inhibits the synthesis of mevalonic acid. The effects of LOV on the cell cycle progression of the human bladder carcinoma T24 cell line expressing activated p21ras were investigated. At a concentration of 2-10 microM, LOV ar...

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Detalhes bibliográficos
Main Authors: Jakóbisiak, M, Bruno, S, Skierski, J S, Darzynkiewicz, Z
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51505/
https://ncbi.nlm.nih.gov/pubmed/1673788
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